The continuing efforts of state colleges and universities in the Philippines to obtain ISO 9001:2015 Certification and recertification have raised speculations on its supposed benefits. This has resulted to the growing interest in determining the impact of the certification efforts in the delivery of quality higher education services in selected state university specifically in Region III. The research employed the quantitative descriptive correlational research design perspective with the survey questionnaire as the primary data collection tool from the 400 students and faculty respondents who were selected randomly using the quota sampling technique. The researcher found out that the state universities generally were progressing towards Level III institutional accreditation, had been in SUC Level III in the past two years, were not yet recognized as either Center of Excellence or Development, had a large number of student enrollment and with the adequate number of faculty members and non-teaching personnel. The respondents assessed the practices under ISO 9001 Certification as highly practiced. The respondents assessed the indicators for Quality Service practices as very evident. There was a significant difference in the assessment of the respondents with regard to the subcategories/dimensions on the Present Status of SUCs on the Quality Service Practices to the SUC‟s profile variable. There was a significant difference on the assessment of the respondents towards dimensions on ISO 9001 practices of SUC‟s profile variables. There was a significant difference on the assessment of the respondents towards dimensions on ISO 9001 practices of SUC‟s as grouping variables. There was a positive moderate relationship between the Quality Service practices and the ISO 9001 practices of the SUC‟s. An Intervention program was proposed to enhance Quality Services of State Universities in the Region of Central Luzon. Based on the gathered data and findings of the study, the researcher has formulated the following recommendations, possible conduct of further research on the ISO 9001:2015 practices and utilizing mixed methods may be conducted to validate the findings of this study. Qualitative methods can enrich the understanding obtained from data in the study, that the proposed intervention plan is encouraged to be implemented which aims to improve the quality service practices of the state universities, universities are encouraged to establish a comprehensive and intensive research program by establishing an in-service training for faculty to enhance their research and statistics capabilities, the leadership of the universities may vigorously pursue innovative practices through research, the top management may consider the provision of incentives to research aimed at generating institutional knowledge that would lead to better services, and for future researcher/s, a replication of the study with an in-depth and wider scope in order validate the salient findings obtained in the study.